Paychex Payroll Services South Carolina

Paychex offers payroll processing in South Carolina through different locations. Whether you are looking for payroll services in Charleston or human resource services in Columbia, our local offices are available to help. Select a Paychex South Carolina location to view contact information and get started.
Paychex Inc. Greenville, 37 Villa Road Suite 101, Greenville, South Carolina 29615, (864) 213-4240
Paychex Inc. Charleston, 4400 Leeds Avenue, Suite 175, North Charleston, South Carolina 29405, (843) 577-8416
Paychex Inc. Columbia, 3710 Landmark Dr Suite 304, Columbia, South Carolina 29204, (866) 553-4183
Office Locations