Paychex HR and Payroll Services in South Carolina
Whether you are looking for payroll services in Greenville or human resource services in Charleston, Paychex can help employers from conveniently located offices in South Carolina. Select the Paychex location nearest you from the map or select a branch from the list below to get started.
Request a free quotePaychex South Carolina Locations
Customer Support in South Carolina
Get help with a wide variety of topics, from login support for our online payroll software to contacting Paychex service teams.
View Support OptionsHow do you know you’re choosing a reputable payroll and HR company in South Carolina to fit your needs?
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Efficient and cost-effective
Paychex delivers superior payroll services by keeping your payroll information safe and secure. Our highly trained experts ensure a smooth transition, leaving more time to make sure your business remains on the go.
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All-in-one HR
We offer products and HR services in South Carolina beyond payroll including workers’ compensation, health insurance, 401(k) administration, and time and attendance solutions.
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Compliance expertise
Our team of compliance experts cycles through the ever-changing South Carolina regulations and tax laws to help you keep up with the issues that matter to your business.

HR and Payroll Resources for your South Carolina Business
Visit Paychex WORX to find more resources such as these to help you solve your company’s payroll and HR issues, including compliance with South Carolina regulations and tax laws. Discover the benefits of outsourcing as you continue your research into HR and payroll outsourcing solutions.